Journal of Applied Medical Sciences

Albuminuria does not Affect the Level of Low-density Lipoprotein Cholesterol in Patients with Stage 5 Chronic Kidney Disease

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• Abstract

  Chronic kidney disease is a major public health problem. Patients with stage 5 chronic kidney disease on dialysis have 3- to 30-fold increase in mortality.The risk of cardiovascular disease varies depending on the type of lipid abnormalities, the target population, the cause of renal disease, and the degree of reduction in glomerular filtration rate. In patients with pre-existing cardiovascular disease, the presence of chronic kidney disease is associated with an increased risk of cardiovascular events. Plasma total cholesterol is usually normaland only occasionally elevated in end stage renal disease patients. This study was carried out at renal clinic of King Abuulaziz hospital and ALNoor specialist hospital in holy Makkah district. Thirty adult male patients with stage 5 chronic kidney disease were randomly selected. Low-density lipoprotein cholesterol concentration was measured using automated spectrophotometer machine. Urinary dipsticks (Multistix) were used to test the presence of albumin in urine. The data were recorded and SPSS test was used to analyze the results. Patients with stage 5 chronic kidney disease with albuminuria have normal concentration of low-density lipoprotein cholesterol. This study concludes that, the presence of albuminuria in patients with stage 5 chronic kidney disease, does not elevate the concentration of low-density lipoprotein cholesterol.